Figure 3.

Once animal’s met criterion in the final signal detection task, the factor of biological sex had a significant effect on percent accuracy and an animal’s response profile. (A) Both male and female animals, regardless of genotype, exhibited a linear increase in percent accuracy across test sessions. However, the rate of increase in percent accuracy occurred more slowly in female animals relative to male animals. (B) Female animals displayed a decreased response rate relative to male animals on all response types (i.e., false alarms, hits, misses and correct rejections). There was no compelling evidence for any effect of the HIV-1 transgene on either percent accuracy or an animal’s response profile once the task was well acquired.