Table 2.
Genes detected for persister formation in this study.
| Gene ID | Gene | Function | Parent | Persister- | Persister- |
|---|---|---|---|---|---|
| name | strain | exponential | stationary | ||
| culture | culture | ||||
| Regulators | |||||
| USA300HOU_2034, USA300HOU_2035 | agrCA | Two-component system | USA500 | – | ↑ |
| NWMN_1945, NWMN_1946 | agrCA | Two-component system | Newman | – | ↑ |
| SAOUHSC_02264, SAOUHSC_02265 | agrCA | Two-component system | HG003 | – | ↑ |
| USA300HOU_2033 | agrD | Signal peptide precursor | USA500 | – | ↑ |
| USA300HOU_nc0020 | RNAIII | Regulatory RNA, includes hld coding sequence | USA500 | – | ↓ |
| USA300HOU_2123 | luxS | Quorum sensing | USA500 | – | – |
| Transcription regulators | |||||
| USA300HOU_0680, USA300HOU_0681 | graRS | Two-component system | USA500 | – | – |
| USA300HOU_1350, USA300HOU_1349 | arlRS | Two-component system | USA500 | – | – |
| Metabolism genes | |||||
| USA300HOU_0336 | nanK | ManNAc kinase | USA500 | – | ↓ |
| USA300HOU_2311 | hutU | Urocanate hydratase | USA500 | – | – |
| USA300HOU_2379 | narG | Nitrate reductase | USA500 | – | – |
| NWMN_2534 | arcA | Arginine deiminase | Newman | – | – |
| NWMN_2530 | arcR | Arginine metabolism regulator | Newman | – | – |
| NWMN_2060 | mtlD | mannitol-1-phosphate 5-dehydrogenase | Newman | – | – |
| NWMN_0122 | imrP | Transporter | Newman | – | – |
| NWMN_2082 | rhbC | Sialic synthase | Newman | – | – |
| NWMN_0132 | ipdC | Indole-3-pyruvate decarboxylase | Newman | – | |
↑, increase; ↓, decrease; –, no significant difference.