Table 6.

Sensitivities and specificities of the ADOS-2-PL (calculated to differentiate the ASD group and the Control group).

Module	Algorithm	Cut-off∗	Sensitivity (%)	Specificity (%)	Positive predictive value	ROC curve (AUCa, 95% CIb)
Toddler Module	All younger/older with few to no words	14	96	95	0.96	0.98 (0.94-1.00)
		11	96	91	0.92
	Older with some words	12	71	94	0.83	0.87 (0.71-1.00)
		10	71	88	0.71
Module 1	Few to no words	13	92	82	0.96	0.99 (0.96-1.00)
	Some words	9	93	83	0.82	0.98 (0.95-1.00)
Module 2	Younger than 5 years	7	91	96	0.95	0.97 (0.94-1.00)
	Aged 5 years or older	6	84	75	0.79	0.91 0.81–1.00)
Module 3		7	90	81	0.83	0.91 0.84–0.98)
Module 4		6	92	74	0.77	0.88 (0.80–0.95)

^∗For Modules 1–4 a single cutoff score has been provided; for Toddler Module where results are converted to the three-point Ranges of concern scale two cut-offs has been provided. ^aArea under the curve. ^bConfidence intervals.