Table 3.

PREP2 algorithm accuracy, positive and negative predictive values

	PPV (95% CI)	NPV (95% CI)	Accuracy for SAFE ≥ 5	Accuracy for SAFE < 5
PREP2: Overall accuracy 75%
Excellent N = 113	79% (73–84%)	83% (75–89%)	78%	70%
Good N = 55	58% (46–68%)	84% (79–88%)
Limited N = 16	86% (44–98%)	95% (93–97%)
Poor N = 23	91% (73–98%)	99% (96–100%)
With MRI: Overall accuracy 75%
Excellent N = 113	79% (73–84%)	83% (75–89%)	78%	70%
Good N = 55	58% (46–68%)	84% (79–88%)
Limited N = 16	73% (46–89%)	100% (97–100%)
Poor N = 23	100%	92% (82–96%)
With no TMS, and no TMS or MRI: Overall accuracy 71%
Excellent N = 113	79% (73–84%)	83% (75–89%)	78%	55%
Good N = 55	53% (41–64%)	82% (77–85%)
Limited N = 16	No predictions	92%
Poor N = 23	64% (50–75%)	99% (96–100%)