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CT-FLCN has structural similarity to DENN domain proteins. A) Crystal structure of carboxy-terminal (CT) domain of FLCN at 2 Å resolution. Two FLCN molecules are in the asymmetric unit. The N-terminus is blue and the C-terminus is red. B) CT-FLCN is structurally similar to the DENN domain of DENN1B protein. CT-FLCN is in blue and DENN domain of DENN1B is in magenta. Adapted from (Nookala et al., 2012).
