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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Acta Biomater. 2017 Sep 30;64:50–58. doi: 10.1016/j.actbio.2017.09.042

Figure 4.

Figure 4

Change in maximum stretches corresponding to 100 kPa equibiaxial Cauchy stress with age for subjects with (red) and without (blue) diabetes (DM). Solid lines represent longitudinal direction, while dashed lines represent circumferential direction. Note that while FPAs stiffen in both longitudinal and circumferential directions, longitudinal stiffening occurs faster resulting in the overall more isotropic behavior of older FPAs. Note too that while longitudinal stiffening of FPAs with DM generally follows that of non-diabetic FPAs, diabetic arteries are significantly stiffer than non-diabetic arteries circumferentially even at younger ages.