Table 2.

Studies evaluating oxytocin effects on social cognition.

Authors	N	Gender	Duration	Design	Setting	Dosing	Administration	Social cognition measures	Outcomes
Averbeck et al., 2012	Exp 1: 30 SZ, 29 HC Exp 2: 21 SZ	Exp 1: M+F Exp 2: M	Single dose	Exp 1: SZ vs HCs Exp 2: crossover	Outpt	24IU	Supervised	Hexagon emotion discrimination test	OT improved emotion recognition in SZ
Davis et al., 2013	23 SZ OT=11, PL=12	M	Single dose	Between	Outpt	40IU	Self	TASIT EPTT Half-PONS Ekman stimuli	OT improved high level social cognition in SZ No improvement in low level or overall social cognition
Fischer-Shofty et al., 2013	35 SZ 48 HC	M+F	Single dose	Within	Outpt	24IU	Supervised	IPT	OT improved kinship recognition in SZ
Goldman et al., 2011	13 SZ 11 HC	M+F	Single dose	Within	Outpt	10 IU 20IU	Supervised	Ekman stimuli (perceived intensity) Benton Facial Discrimination Test	10 IU decreased emotion recognition 20 IU improved emotion recognition in polydipsic SZ
Guastella et al., 2015	21 SZ	M	Single dose	Within	Outpt	24 IU	Supervised	DANVA FEEST RMET FBPSTL Hinting task Faux Pas Recognition	OT improved performance on higher order social cognition Improved paralinguistic subscomponent of DANVA
Horta de Macedo et al., 2014	20 SZ 20 HC	M	Single dose	Within	Outpt	48 IU	Supervised	Facial Emotion Matching	OT did not improve emotion matching in SZ or HCs
Shin et al., 2015	16 SZ 15 HC	M	Single dose	Within	Outpt	40IU	Supervised	Emotion Recognition Test (C-KFEE stimuli)	OT attenuated amygdala activity for emotional faces in SZ OT increased amygdala activity in HCs
Woolley et al., 2014	29 SZ 31 HC	M	Single dose	Within	Outpt	40 IU	Supervised	RMET TASIT	OT improved controlled social cognition in SZ