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. 2017 Sep 29;6(8):766–772. doi: 10.1530/EC-17-0257

Figure 2.

Figure 2

Biochemical structure of aldosterone, fludrocortisone, cortisol and prednisolone. The changes that give a longer half-life are shown in red. A fluorine atom is present in fludrocortisone, and a double bond in prednisolone is the only difference between these molecules and cortisol.