Table 4.
Three year outcomes for principal sensitivity analysis of 502 patients with confirmed diagnosis of abdominal aortic aneurysm rupture in whom repair was started. Figures are mean differences unless stated otherwise
| Outcome (measure) | No of patients | Estimate (95% CI) | P value* | |
|---|---|---|---|---|
| As randomised (intention to treat) | Complier average causal effect (CACE) | |||
| OR for mortality† | 498 | 0.62 (0.43 to 0.88) | 0.53 (0.34 to 0.84) | 0.008 |
| OR for any reintervention related to the aneurysm | 502 | 1.12 (0.76 to 1.65) | 1.16 (0.69 to 1.94) | 0.58 |
| EQ-5D‡ | 262 | 0.013 (−0.069 to 0.096) | 0.041 (−0.112 to 0.193) | 0.75 |
| QALYs§ | 502 | 0.229 (0.043 to 0.414) | 0.512 (0.084 to 0.940) | 0.016 |
| Total cost (£) | 502 | −2610 (−6200 to 978) | −6126 (−14336 to 2083) | 0.154 |
| Incremental net benefit (£) | 502 | 9484 (2828 to 16 140) | 21 528 (5999 to 37 057) | 0.003 |
OR=odds ratio.
*Same for intention to treat and CACE estimates, but magnitude of effect might be different.
†4 patients lost to follow-up for mortality by 3 years.
‡For EQ-5D-3L scores, number of patients is total number eligible for follow-up (that is, still alive and not lost to follow-up). EQ-5D missing for 33 (22%) EVAR patients and 21 (19%) open repair patients.
§Includes patients who died.