Table 1. miRNAs analyzed by microarray.
Name | Fold change injury versus sham | P-value | Genomic coordinates |
---|---|---|---|
mmu-miR-292-3p | 2.079233 | 0.049315 | chr7: 3 219 189–3 219 270 |
mmu- miR-103 | 0.419844 | 0.037357 | chr11: 35 782 396–35 782 481 |
mmu-let-7b | 0.379569 | 0.040591 | chr15: 85 707 319–85 707 403 |
mmu-miR-151 | 0.298605 | 0.048223 | chr15: 73 254 815–73 254 882 |
mmu-miR-352 | 0.370564 | 0.046623 | & |
mmu-miR-26b | 0.317149 | 0.02567 | chr1: 74 394 310–74 394 394 |
mmu-miR-182 | 0.417398 | 0.007855 | chr6: 30 165 918–30 165 992 |
mmu-miR-31* | 0.248849 | 0.005678 | chr4: 88 910 557–88 910 662 |
mmu-miR-192 | 0.317994 | 0.005864 | chr19: 6 264 844–6 264 932 |
mmu-let-7d | 0.474344 | 0.026367 | chr13: 48 536 012–48 536 114 |
mmu-miR-429 | 0.251106 | 0.013855 | chr4: 156 053 905–15 6053 987 |
mmu-miR-32 | 0.317152 | 0.036267 | chr4: 56 895 229–56 895 298 |
mmu-miR-192* | 0.267506 | 0.022734 | chr19: 6 264 844–6 264 932 |
mmu-miR-96 | 0.25604 | 0.023989 | chr6: 30 169 446–30 169 551 |
mmu-miR-15b | 0.307694 | 0.021726 | chr3: 69 009 772-–69 009 835 |
mmu-miR-16 | 0.349734 | 0.041569 | chr14: 61 631 880–61 631 972 |
mmu-let-7a | 0.434087 | 0.047695 | chr13: 48 538 179–48 538 272 |
mmu-miR-30b-5p | 0.425581 | 0.035156 | chr15: 68 337 415–68 337 510 |
mmu-miR-378 | 0.40383 | 0.003153 | chr18: 61 397 835–61 397 900 |
&: only experimental evidence. Not found in mouse genome. Confidence:undefined.
Microarray analysis identified 19 differentially expressed miRNAs in response to intestinal I/R, all of which exhibited a P-value <0.05 calculated by t-test when compared with the sham group (n=5 per group)