Table 2. Intestinal I/R-responsive miRNA candidates were confirmed by RT-qPCR.
miRNA |
Relative expression () |
P-value | Fold change | |
---|---|---|---|---|
Sham group | Injury group | |||
mmu-miR-26b | 0.98±0.02 | 0.637±0.06 | 0.001 | 1.54 |
mmu-miR-16 | 1.48±0.42 | 0.38±0.06 | 0.011 | 3.90 |
mmu-let-7b | 1.02±0.06 | 0.30±0.05 | 0.001 | 3.40 |
mmu-miR-103 | 1.00±0.2 | 0.35±0.05 | 0.06 | 2.86 |
mmu-miR-15b | 0.85±0.19 | 0.35±0.09 | 0.015 | 2.43 |
mmu-miR-192 | 0.96±0.04 | 0.22±0.06 | 0.001 | 4.36 |
mmu-miR-182 | 0.87±0.14 | 0.13±0.02 | 0.001 | 6.69 |
mmu-let-7a | 1.08±0.08 | 0.21±0.04 | 0.001 | 5.14 |
mmu-miR-378 | 0.88±0.17 | 0.26±0.06 | 0.04 | 3.38 |
A fold change of at least 1.5 and putative target mRNAs that were linked to cell death were identified (n=5 per group)