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. 2017 Oct 12;8(10):e3120. doi: 10.1038/cddis.2017.509

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Copyright © 2017 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Infiltration of F4/80s and neutrophils, and expression of MDM-4 and p53 in VAN-induced AKI in MBD2 KO and wild-type mice. Wild-type and MBD2 KO littermate mice were injected with 600 mg/kg VAN (n=8) or saline as control for 7 days. (a) Immunohistochemical staining of macrophages, neutrophils and expression of MDM-4 and p53 (original magnification × 200). (b) Quantitation of positive staining cells per cross-sectional area. Data were expressed as means±S.D.; ^#P<0.05 versus Saline group; *P<0.05 versus VAN group. Data are the representative of at least four separate experiments