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. 2017 Oct 26;8(10):e3154. doi: 10.1038/cddis.2017.525

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Copyright © 2017 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Antiproliferative effects of miR-629 on pancreatic cancer cells in vitro. (a) MTT experiment. Cell viability was significantly increased in cells with overexpression of miR-629 compared with control cells in a time-dependent manner. Values represent means±S.D. (*P<0.01). (b) Cell cycle assay. Cell cycle analysis indicated an increased population of cells at the G2/M+S phase by miR-629 overexpression. The experiment was repeated three times (*P<0.05). (c) Clone-formation assay. The effect of miR-629 overexpression on cell proliferation was evaluated with crystal violet staining. Values represent the means±S.D. of three experiments from three independent tests (*P<0.05). (d) Analysis of sphere formation. miR-629 accelerated sphere formation of pancreatic carcinoma cells (*P<0.05)