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Pathological but not physiological stress promotes MG53 expression. A, MG53 expression levels were significantly increased by 3-fold and 2.76-fold, respectively, in compensated hypertrophy and heart failure following 5-week pressure overload cardiac stress. **, p< 0.01 vs sham group. B, MG53 expression levels were not altered in mice following 4 weeks exercise training.
