Supplemental Figure S5.

WT or GFAP-TK-Tg mice were treated with carbon tetrachloride (three administrations, 3 days apart). This was followed by termination of carbon tetrachloride and treatment with PBS for 10 days. Mice were then injected ConA or vehicle (PBS) and euthanized 6 hours later. Vehicle (oil/PBS) or carbon tetrachloride treatment, followed by ConA treatment, shows similar hepatic injury, as determined by histopathological examination of hematoxylin and eosin–stained liver sections of B6-WT or GFAP-TK-Tg mice. Scale bar = 100 μm.