TABLE 1.
Number of studies | WMD (95% CI) | P value* | Q value | P value** | I2 | |
Study duration, d | ||||||
SBP | ||||||
<14 | 26 | −2.67 (−4.03, −1.31) | 0.001 | 45.7 | 0.007 | 45.4 |
≥14 | 17 | −5.11 (−6.63, −3.60) | 0.001 | 9.30 | 0.90 | 0 |
DBP | ||||||
<14 | 26 | −0.91 (−1.65, −0.16) | 0.017 | 18.8 | 0.81 | 0 |
≥14 | 17 | −1.32 (−1.97, −0.68) | 0.001 | 4.37 | 0.99 | 0 |
Dose of beetroot, mL/d | ||||||
SBP | ||||||
70 and 140 | 14 | −2.37 (−4.52, −0.22) | 0.03 | 18.0 | 0.15 | 28.0 |
250 | 18 | −3.22 (−4.87, −1.58) | 0.001 | 22.2 | 0.17 | 23.3 |
500 | 11 | −4.78 (−5.81, −3.73) | 0.001 | 8.93 | 0.53 | 0 |
DBP | ||||||
70 and 140 | 14 | −0.29 (−1.39, 0.79) | 0.59 | 9.13 | 0.76 | 0 |
250 | 18 | −1.48 (−2.69, −0.27) | 0.016 | 5.54 | 0.99 | 0 |
500 | 11 | −2.14 (−3.21, −1.09) | 0.001 | 7.48 | 0.68 | 0 |
NO3 content of beetroot, mg/100 mL per day | ||||||
SBP | ||||||
<150 | 12 | −4.63 (−5.74, −3.52) | 0.001 | 11.6 | 0.38 | 5.70 |
151–249 | 14 | −3.43 (−5.11, −1.76) | 0.001 | 20.6 | 0.19 | 22.6 |
≥250 | 17 | −2.37 (−4.52, −0.22) | 0.030 | 18.0 | 0.15 | 28.0 |
DBP | ||||||
<150 | 12 | −2.11 (0.315, −1.07) | 0.001 | 7.60 | 0.74 | 0 |
151–249 | 14 | −1.50 (−2.74, −0.25) | 0.018 | 5.53 | 0.99 | 0 |
≥250 | 17 | −0.29 (−1.39, 0.79) | 0.59 | 9.13 | 0.76 | 0 |
Types of placebo | ||||||
SBP | ||||||
NO3-depleted beetroot | 27 | −2.91 (−4.34, −2.54) | 0.001 | 37.2 | 0.07 | 30.1 |
Others2 | 16 | −4.57 (−5.55, −3.59) | 0.001 | 14.5 | 0.48 | 0 |
DBP | ||||||
NO3-depleted beetroot | 27 | −0.71 (−1.96, 0.14) | 0.10 | 13.7 | 0.97 | 0 |
Others2 | 16 | −2.10 (−3.08, −1.12) | 0.001 | 9.79 | 0.83 | 0 |
To assess statistical heterogeneity, the I2 statistic and Cochran’s Q statistic were used according to specific categories (low = 25%, moderate = 50%, and high = 75%) and significance level (P < 0.10), respectively. *, P for WMD; **, P for Q value. DBP, diastolic blood pressure; SBP, systolic blood pressure; WMD, weighted mean difference.
Blackcurrant juice (n = 10), low-calorie juice (n = 5), and control diet for NO3 (n = 1).