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. 2017 Nov 7;8(6):830–838. doi: 10.3945/an.117.016717

TABLE 1.

Meta-analysis of the mean difference of blood pressure between beetroot-supplemented and control groups1

Number of studies WMD (95% CI) P value* Q value P value** I2
Study duration, d
 SBP
  <14 26 −2.67 (−4.03, −1.31) 0.001 45.7 0.007 45.4
  ≥14 17 −5.11 (−6.63, −3.60) 0.001 9.30 0.90 0
 DBP
  <14 26 −0.91 (−1.65, −0.16) 0.017 18.8 0.81 0
  ≥14 17 −1.32 (−1.97, −0.68) 0.001 4.37 0.99 0
Dose of beetroot, mL/d
 SBP
  70 and 140 14 −2.37 (−4.52, −0.22) 0.03 18.0 0.15 28.0
  250 18 −3.22 (−4.87, −1.58) 0.001 22.2 0.17 23.3
  500 11 −4.78 (−5.81, −3.73) 0.001 8.93 0.53 0
 DBP
  70 and 140 14 −0.29 (−1.39, 0.79) 0.59 9.13 0.76 0
  250 18 −1.48 (−2.69, −0.27) 0.016 5.54 0.99 0
  500 11 −2.14 (−3.21, −1.09) 0.001 7.48 0.68 0
NO3 content of beetroot, mg/100 mL per day
 SBP
  <150 12 −4.63 (−5.74, −3.52) 0.001 11.6 0.38 5.70
  151–249 14 −3.43 (−5.11, −1.76) 0.001 20.6 0.19 22.6
  ≥250 17 −2.37 (−4.52, −0.22) 0.030 18.0 0.15 28.0
 DBP
  <150 12 −2.11 (0.315, −1.07) 0.001 7.60 0.74 0
  151–249 14 −1.50 (−2.74, −0.25) 0.018 5.53 0.99 0
  ≥250 17 −0.29 (−1.39, 0.79) 0.59 9.13 0.76 0
Types of placebo
 SBP
  NO3-depleted beetroot 27 −2.91 (−4.34, −2.54) 0.001 37.2 0.07 30.1
  Others2 16 −4.57 (−5.55, −3.59) 0.001 14.5 0.48 0
 DBP
  NO3-depleted beetroot 27 −0.71 (−1.96, 0.14) 0.10 13.7 0.97 0
  Others2 16 −2.10 (−3.08, −1.12) 0.001 9.79 0.83 0
1

To assess statistical heterogeneity, the I2 statistic and Cochran’s Q statistic were used according to specific categories (low = 25%, moderate = 50%, and high = 75%) and significance level (P < 0.10), respectively. *, P for WMD; **, P for Q value. DBP, diastolic blood pressure; SBP, systolic blood pressure; WMD, weighted mean difference.

2

Blackcurrant juice (n = 10), low-calorie juice (n = 5), and control diet for NO3 (n = 1).