Table 2.
Diagnosis of type 1 myocardial infarction using high sensitivity cardiac troponin
| Type 1 myocardial infarction | Total | Diagnostic parameter, % (95% CI) | |||||
|---|---|---|---|---|---|---|---|
| Yes | No | Sensitivity | Specificity | Negative predictive value | Positive predictive value | ||
| Unselected cohort (n=1054) | |||||||
| High sensitivity cardiac troponin >99th centile: | - | - | - | 100 (80.5 to 100) | 87.7 (85.6 to 90.0) | 100 (99.6 to 100) | 11.8 (7.0 to 18.2) |
| Yes | 17 | 127 | 144 | ||||
| No | 0 | 910 | 910 | ||||
| Total | 17 | 1037 | 1054 | ||||
| Selected cohort, UK (n=5815) | |||||||
| High sensitivity cardiac troponin >99th centile: | - | - | - | 100 (99.6 to 100) | 88.5 (87.6 to 89.4) | 100 (99.9 to 100) | 59.7 (57.0 to 62.2) |
| Yes | 843 | 570 | 1413 | ||||
| No | 0 | 4402 | 4402 | ||||
| Total | 843 | 4972 | 5815 | ||||
| Selected cohort, US (n=1631) | |||||||
| High sensitivity cardiac troponin >99th centile: | - | - | - | 100 (94.7 to 100) | 77.8 (75.7 to 79.8) | 100 (99.7 to 100) | 16.4 (13.0 to 20.3) |
| Yes | 68 | 347 | 415 | ||||
| No | 0 | 1216 | 1216 | ||||
| Total | 68 | 1563 | 1631 | ||||