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. 2017 Dec;363(3):314–323. doi: 10.1124/jpet.117.244392

Fig. 1.

Fig. 1.

(Left panels) Dose-effect functions for AEA administered either intramuscularly (open triangle, n = 4) or intravenously (closed inverted-triangle, n = 1) in subjects trained to discriminate 0.01 mg/kg AM4054 from vehicle. Abscissae, cumulative dose, log scale; ordinate, percentage of responses on the AM4054-associated lever (top left panel), response rate (bottom left panel). Symbols left of the abscissae break indicate performance during vehicle (V) and AM4054 (AM) control sessions. Points represent averages (±S.E.M.) for the groups of subjects. (Right panels) Dose-effect functions for 2-AG, administered either intramuscularly (open diamond, n = 4) or intravenously (closed square, n = 3) in subjects trained to discriminate 0.01 mg/kg AM4054 from vehicle. Abscissae, cumulative dose, log scale; ordinate, percentage of responses on the AM4054-associated lever (top left panel), response rate (bottom left panel). Symbols left of the abscissae break indicate performance during V and AM control sessions. Points represent averages (±S.E.M.) for the groups of subjects.