Skip to main content
. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Clin Cancer Res. 2017 Jul 14;23(21):6686–6696. doi: 10.1158/1078-0432.CCR-17-1057

Figure 2. Sarcomatoid RCC segregates according to parent subtype.

Figure 2

Sarcomatoid RCC (SRCC) of different parent subtypes (SccRCC, SPapRCC, and SChRCC) demonstrates (A) similar mutational burdens compared to non-sarcomatoid RCC (RCC) of different parent subtypes (ccRCC, PapRCC, and ChRCC). SRCCs segregate according to parent subtype, as shown by an unsupervised clustering analysis of (B) copy number, 1500 top genes; and (C) mRNA expression, 1000 genes. (D) Mutations of 3p21–25 tumor suppressor genes are confined to SccRCC.