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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Clin Cancer Res. 2017 Jul 14;23(21):6686–6696. doi: 10.1158/1078-0432.CCR-17-1057

Figure 4. Sarcomatoid RCC shows a distinct transcriptional program.

Figure 4

A. Sarcomatoid RCC shows enrichment of TGFβ1 signaling across different parent subtypes. B. Sarcomatoid ccRCC shows differential regulation of various signaling pathways compared to advanced-stage (stages III and IV) non-sarcomatoid ccRCC. C. Expression differences between the E- and S- components of sarcomatoid ccRCC translate into discrete pathway alterations. Barplots indicate number of cases analyzed across each contrast.