Table 1.

Fewer concurrent loss of heterozygosity and mutations of the VHL and PBRM1 genes in sarcomatoid ccRCC than in ccRCC, by P value (odds ratio)

	3p 21–25 gene
Test	VHL	BAP1	SETD2	PBRM1
SccRCC vs grade 1 ccRCC	3.97E-02 (0.13)	1 (1)	1 (1)	1.93E-03 (0.04)
SccRCC vs grade 2 ccRCC	2.7E-06 (0.14)	1 (1.03)	2.11E-01 (0.43)	1.53E-05 (0.11)
SccRCC vs grade 3 ccRCC	1.49E-06 (0.13)	1 (1.01)	5.72E-01 (0.63)	1.66E-04 (0.14)
SccRCC vs grade 4 ccRCC	5.25E-02 (0.3)	6.97E-01 (0.58)	1 (1.21)	7.99E-03 (0.17)
SccRCC vs all ccRCC	1.79E-06 (0.15)	1 (0.96)	4.52E-01 (0.56)	1.79E-05 (0.13)