Table 2.
Interactions between TCR and MHC in the F50–GIL–HLA-A2 and JM22–GIL–HLA-A2 complexes
| Hydrogen bonds | van der Waals contacts | Hydrogen bonds | van der Waals contacts | |
|---|---|---|---|---|
| HLA-A2 | F50 | F50 | JM22 | JM22 |
| R65H | Q58β | |||
| K66H | N98α | |||
| K68H | D56β | |||
| A69H | I96β | D56β | ||
| G99β | ||||
| Q72H | M50β | I53β | ||
| G99β | N55β | |||
| T73H | I53β | |||
| R75H | N55β | |||
| V76H | M50β | I53β | ||
| T80H | A80H (Oγ1) N51β (Nδ2) | N51β | ||
| Y84H | Y84H(OH) E30β(Oϵ2) | E30β | ||
| K146H | L95β | |||
| A149H | Y101β | |||
| A150H | R52α | A150H(O) R98β(Nϵ) | R98β | |
| L96β | A150H(O) R98β(Nη2) | Y101β | ||
| W99β | ||||
| H151H | R52α | V51α | ||
| R98β | ||||
| Y101β | ||||
| V152H | W99β | R98β | ||
| E154H | E154H (Oϵ2) N54α (Nδ2) | N54α | S31α | |
| V51α | ||||
| Q155H | Q155H (Nϵ2) N32α (Nδ2) | N32α | Q155H (Oϵ1) R98β (Nη1) | S31α |
| Q155H (Oϵ1) S53α (Oγ) | R52α | Q155H (Oϵ1) R98β (Nη2) | G94α | |
| S53α | R98β | |||
| N54α | S100β | |||
| W99β |