Table 3.

Summary of EEG findings in DS and AD.

Authors	# of participants	Method	Findings
Babiloni et al. (2010)	45 DS subjects, 45 age-matched cognitively normal subjects	Eyes-closed resting EEG data collected, with EOG.	Central, parietal, occipital, and temporal cortex had alpha and beta rhythms with lower amplitude in DS, while delta rhythms were higher in amplitude in DS.
d'Orsi et al. (2014)	12 with DS/AD/myoclonic epilepsy, over the age of 40	Long-term EEG monitoring during sleep and wake, with EMG and EKG.	3 stages of epilepsy were found: diffuse abnormalities during sleep with dementia onset, myoclonic epilepsy, and finally non-epileptic myoclonus with severe dementia.
Salem et al. (2015)	21 with DS and dementia, 16 with DS and no dementia	EEG during wake resting state, with EOG and EKG.	Decreased theta band frequencies in several regions of the brain are correlated with cognitive deterioration based on the Dementia Screening Questionnaire in Intellectual Disability.

Abbreviations: AD, Alzheimer's disease; DS, Down syndrome; EEG, electroencephalography; EKG, electrocardiography; EMG, electromyography; EOG, electrooculography.