Observed intensity changes in bacteria-related metabolites from cell extracts. Exampled metabolites include leucinic acid, phenyllactic acid, heptaprenyl diphosphate and hydroxyphenylpyruvic acid sulfate. *: p < 0.05, T2 vs C; ¥: p < 0.05, T2 vs T1; Δ: p < 0.05, T1 vs C. Significant changes were observed in all four metabolites in the treated groups compared with controls.