Table 3.

Univariable and Multivariable Analysis of Demographics and Geriatric Syndromes Associated with Secondary Prevention Medication Initiation after Resident Admission to Nursing Home after Acute Myocardial Infarction (N=11,192)

Characteristic	Univariable Association (POR, 95% CI)	Multivariable Association (POR, 95% CI)1
Age in years
65 to <75	Reference	Reference
75 to <85	0.78 (0.70–0.87)	0.79 (0.70–0.89)
85 to <95	0.62 (0.55–0.68)	0.66 (0.58–0.74)
≥95	0.44 (0.38–0.51)	0.48 (0.40–0.57)
Sex
Male	Reference	Reference
Female	0.80 (0.74–0.87)	0.88 (0.80–0.96)
Race
White, non-Hispanic	Reference	Reference
Black, non-Hispanic	1.19 (1.07–1.32)	1.17 (1.03–1.33)
Hispanic	1.10 (0.92–1.31)	1.07 (0.87–1.31)
Other	1.07 (0.72–1.38)	1.08 (0.81–1.45)
Region
Northeast	Reference	Reference
Midwest	0.79 (0.72–0.87)	0.81 (0.72–0.91)
South	0.66 (0.60–0.72)	0.69 (0.62–0.77)
West	0.82 (0.73–0.93)	0.80 (0.68–0.93)
Caribbean	0.77 (0.54–1.08)	0.78 (0.53–1.14)
CHESS score (health instability)
No instability	Reference	Reference
Minimal	0.91 (0.84–0.98)	0.96 (0.87–1.05)
Low	0.86 (0.78–0.96)	0.90 (0.79–1.02)
Moderate to very high	0.77 (0.62–0.95)	0.92 (0.73–1.17)
Cognitive impairment
Cognitively intact	Reference	Reference
Mild	0.84 (0.76–0.94)	0.94 (0.84–1.06)
Moderate to severe	0.67 (0.60–0.74)	0.79 (0.70–0.89)
Dependence in activities of daily living
Independent/limited	Reference	Reference
Extensive	0.92 (0.85–1.00)	0.88 (0.81–0.97)
Dependent	0.79 (0.72–0.87)	0.77 (0.69–0.86)
Do not resuscitate order
No	Reference	Reference
Yes	0.74 (0.69–0.79)	0.90 (0.83–0.98)

Abbreviations: POR, proportional odds ratio; COPD, Chronic Obstructive Pulmonary Disease; CHF, Congestive Heart Failure; CCU/ICU, Coronary Care Unit/Intensive Care Unit.

¹Multivariable analyses also adjusted for a wide range of variables not shown here including demographics, clinical conditions, baseline medications, geriatric syndromes, AMI characteristics, and nursing home characteristics; see Supplementary Table S4 for complete list.