Table 4.
Univariable and Multivariable Analysis of Clinical Conditions and Myocardial Infarction Characteristics Associated with Secondary Prevention Medication Initiation after Resident Admission to Nursing Home after Acute Myocardial Infarction (N=11,192)
| Characteristic | Univariable Association (POR, 95% CI) |
Multivariable Association (POR, 95% CI)1 |
|---|---|---|
| Atrial fibrillation | ||
| No | Reference | Reference |
| Yes | 0.90 (0.83–0.97) | 0.90 (0.82–0.98) |
| Angina pectoris | ||
| No | Reference | Reference |
| Yes | 0.32 (0.29–0.36) | 0.32 (0.28–0.36) |
| Unstable angina | ||
| No | Reference | Reference |
| Yes | 0.78 (0.69–0.87) | 0.63 (0.56–0.72) |
| Asthma | ||
| No | Reference | Reference |
| Yes | 0.97 (0.73–1.30) | 0.97 (0.71–1.32) |
| COPD | ||
| No | Reference | Reference |
| Yes | 0.87 (0.81–0.94) | 0.88 (0.80–0.96) |
| CHF | ||
| No | Reference | Reference |
| Yes | 1.18 (1.11–1.27) | 1.28 (1.18–1.38) |
| Elixhauser score | ||
| 0–2 | Reference | Reference |
| 3–4 | 1.10 (1.02–1.19) | 0.98 (0.89–1.08) |
| ≥5 | 1.12 (1.01–1.25) | 0.98 (0.85–1.13) |
| Length of stay, days | ||
| 0–4 | Reference | Reference |
| 5–9 | 1.16 (1.07–1.26) | 0.94 (0.85–1.04) |
| ≥10 | 1.18 (1.07–1.30) | 0.80 (0.71–0.91) |
| CCU or ICU use, days | ||
| 0 | Reference | Reference |
| 1–3 | 1.57 (1.44–1.72) | 1.33 (1.21–1.47) |
| ≥4 | 1.66 (1.53–1.80) | 1.33 (1.21–1.47) |
| Coronary revascularization2 | ||
| No | Reference | Reference |
| Yes | 2.31 (1.79–2.98) | 1.62 (1.24–2.13) |
Abbreviations: POR, proportional odds ratio; COPD, Chronic Obstructive Pulmonary Disease; CHF, Congestive Heart Failure; CCU/ICU, Coronary Care Unit/Intensive Care Unit.
Multivariable analyses also adjusted for a wide range of variables not shown here including demographics, clinical conditions, baseline medications, geriatric syndromes, AMI characteristics, and nursing home characteristics; see Supplementary Table S4 for complete list.
Coronary revascularization and angioplasty procedures.