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. Author manuscript; available in PMC: 2018 Oct 23.
Published in final edited form as: Curr Biol. 2017 Oct 12;27(20):3120–3131.e4. doi: 10.1016/j.cub.2017.09.011

Figure 3. Asymmetric localization of core PCP protein localization is lost in PCP mutants.

Figure 3

(A–C) E18.5 Vangl2Lp/Lp collecting ducts (DBA, red) stained for (A) Vangl1 (green) and E-Cadherin (blue), (B) Fz6 (red) and E-Cadherin (blue) or (C) Fz3 (red) and E-Cadherin (blue) showing similar proximal and distal localization of Vangl1, Fz6 and Fz3 (arrowheads). (D) E18.5 Fz3−/−; Fz6−/− collecting duct stained for Vangl1 (green) and E-Cadherin (arrowheads). (E) P1 Vangl1,2DKO, Ksp-Cre collecting duct stained for Fz6 (red) and E-Cadherin (blue). Scale bars: 5 μm. See also Figure S3.