Table 4.
WGS finding prompting the clinical action | Clinical Testing Ordered | Findings from Clinical Testing |
---|---|---|
GWAS predicted increased risk for atrial fibrillation | Ambulatory electrocardiographic monitoring, n=1 | Test not completed. Existing medical information used instead. |
GWAS predicted increased risk for aortic aneurysm | Abdominal ultrasound, n=2 | No aortic dilatation identified (n=1); Imaging not completed (n=1) |
CHEK2 variant | Cancer genetics referral, n=1 | Declined by patient |
Two carrier variants | Preconception genetic counseling recommended, n=1 | Not yet completed |