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. 2017 Jul 24;2:20. doi: 10.1186/s40834-017-0047-4

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Tissue plasminogen activator (tPA) converts plasminogen to plasmin, which dissolve the fibrin in the blood clot. Plasminogen activator inhibitor-1 (PAI-1) and Tissue Factor (TF) are procoagulant by inhibiting plasminogen activators and increasing fibrin, respectively [34]. The figure is also separately submitted in a file name “figure1.jpg”