Table 1.
variable | Relative miR-361-5p expression | P-value | |
---|---|---|---|
Low (n = 30) | High (n = 30) | ||
Age | NS | ||
< 50 | 17 | 14 | |
> 50 | 13 | 16 | |
Histological differentiation | NS | ||
Well | 7 | 6 | |
Moderate | 14 | 17 | |
Poor | 9 | 7 | |
ER status | NS | ||
Positive | 16 | 17 | |
Negative | 14 | 13 | |
PR status | NS | ||
Positive | 21 | 14 | |
Negative | 9 | 16 | |
Her-2 status | NS | ||
Positive | 11 | 8 | |
Negative | 19 | 22 | |
Tumor size | P < 0.05 | ||
< 2 cm | 11 | 21 | |
2-5 cm | 12 | 6 | |
> 5 cm | 7 | 3 | |
Lymph node metastasis | P < 0.01 | ||
Yes | 21 | 6 | |
No | 9 | 24 | |
Tumor stage | P < 0.05 | ||
I | 7 | 15 | |
II | 12 | 11 | |
III | 11 | 4 | |
Molecular subtype | NS | ||
Luminal like | 16 | 17 | |
HER-2 positive | 10 | 7 | |
Triple negative | 4 | 6 |
Note: BC patients were divided into miR-361-5p High group and Low group according to the analysis of qRT-PCR detection. NS, not significant between different groups. Differences among variables were evaluated by χ2 or Fisher’s exact χ2 -test