Fig. 3.

Gene set enrichment plot and expression heatmap of corresponding genes in the enriched gene set. Left panels include the running enrichment score throughout the gene set and projection of genes in the geneset to the complete list of genes rank ordered based on signal to noise ratio. On the expression heatmap (columns are eBL tumors and GC B cells, rows are genes in the gene set), dark red represent higher expression while dark blue lower expression. Genes in this enrichment are a set of genes regulated by MYC in eBLs tumor cells relative to GC B cells (ES = 0.45, Nominal P = 0.046, FDR q = 0.118)