Table 1.

Ages of female first degree relatives being 25 years of age or older at cancer, or last age known without cancer, stratified on tested or not, and when tested on results of testing for BRCA2 c.68–7T> A in the 17 families where such information was known

Family	Carriers			Not carriers		Not tested
	Proband	Ages 1st degree female relatives with cancer and relationship	Last age 1st degree female relatives without cancer and relationship	Ages 1st degree female relatives with cancer and relationship	Last age 1st degree female relatives without cancer and relationship	Ages 1st degree female relatives with cancer and relationship	Last age 1st degree female relatives without cancer and relationship
1	Breast ca 55 & 58 yrs	Mother breast ca 38 yrs			61 yrs sister
2	Breast ca 43 yrs					Mother breast ca 40 yrs
3	Ovarian ca 26 yrs					Mother breast ca 78 yrs Sister breast ca 40 yrs
4	Breast ca 35 yrs	Mother breast ca 47 & 68 yrs	39 yrs sister		35 yrs sister
5	Breast ca 38 yrs	Mother breast and ovarian cancer 54 yrs	42 yrs sister		29 yrs sister
6	77 yrs no cancer					Mother ovarian ca 66 yrs Daughter breast cancer 33 yrs
7	Breast ca 44 & 46 yrs			Mother endometrial ca 63 yrs
8	No cancer 36 yrs			Mother breast 55 Sister breast ca 36 yrs
9	Male prostate cancer 47 yrs						Unknown age mother
10	Healthy male		26 yrs daughter 21 yrs daughter			Mother breast ca 35 yrs
11	Breast ca 30 yrs		43 yrs sister			Mother breast ca 64 yrs
12	Breast ca 45 yrs				42 yrs daughter	Sister ovarian ca 43 yrs Mother cervix ca 54 & breast ca 55 yrs
13	Ovarian ca 44 yrs	Sister breast ca 40 yrs	67 yrs mother
14	58 yrs no cancer					Mother breast ca 65 yrs	46 yrs sister
15	No ca 73 yrs					Sister breast ca 67 yrs Sister breast ca 62 yrs
16	59 yrs no cancer					Sister ovarian ca 55 yrs Mother smoker unknown age lung cancer	Unknown age mother
17	45 yrs no ca					Mother breast ca 32 yrs and malignant melanoma 42 yrs

ca cancer, yrs years