Table 3.
The distribution of combinations of Arg399Gln of gene XRCC1 and Arg72Pro of gene TP53 polymorphic markers in Kyrgyz women with BC and controls
| XRCC1/TP53 genotypes | Cases, n (%) | Controls, n (%) | OR (95% CI) | χ2/р |
|---|---|---|---|---|
| Arg399Arg/Arg72Arg | 19 (16) | 27 (26) | Ref. | |
| Arg399Arg/Arg72Pro | 18 (15) | 21 (21) | 1.22 (0.52–2.88) | 0.20/0.65 |
| Arg399Arg/Pro72Pro | 1 (1) | 8 (8) | 0.18 (0.02–1.54) | 2.97/0.085 |
| Arg399Gln/Arg72Arg | 32 (27) | 20 (20) | 2.27 (1.01–5.11) | 3.23/0.07 |
| Arg399Gln/Arg72Pro | 28 (24) | 10 (9) | 3.98 (1.57–10.09) | 7.58/0.0059 |
| Arg399Gln/Pro72Pro | 8 (7) | 4 (4) | 2.84 (0.75–10.81) | 2.46/0.116 |
| Gln399Gln/Arg72Arg | 6 (5) | 6 (6) | 1.42 (0.40–5.09) | 0.29/0.588 |
| Gln399Gln/Arg72Pro | 4 (3) | 5 (5) | 1.14 (0.27–4.80) | 0.03/0.861 |
| Gln399Gln/Pro72Pro | 1 (1) | 1 (1) | 1.42 (0.08–24.18) | 0.06/0.807 |
OR odds ratio, CI confidence interval