Table 5.
The distribution of combinations of Arg72Pro of gene TP53 and T309G of gene MDM2 polymorphic markers in Kyrgyz women with BC and controls
| TP53/MDM2 genotypes | Cases, n (%) | Controls, n (%) | OR (95% CI) | χ2/р |
|---|---|---|---|---|
| Arg72Arg/G309G | 8 (7) | 11(11) | Reference | |
| Arg72Arg/G309T | 36 (31) | 31 (30) | 1.60 (0.57–4.47) | 0.80/0.37 |
| Arg72Arg/T309T | 13 (11) | 11 (11) | 1.63 (0.48–5.47) | 0.62/0.43 |
| Arg72Pro/ G309G | 21 (18) | 11 (11) | 2.63 (0.82–8.43) | 2.69/0.10 |
| Arg72Pro/ G309T | 18 (15) | 19 (19) | 1.30 (0.43–3.98) | 0.22/0.64 |
| Arg72Pro/ T309T | 11 (9) | 6 (6) | 2.52 (0.65–9.71) | 1.84/0.18 |
| Pro72Pro/ G309G | 0 (0) | 6 (6) | 0.10 (0.005–2.11) | 3.72/0.05 |
| Pro72Pro / G309T | 8 (7) | 5 (5) | 2.20 (0.52–9.30) | 1.17/0.28 |
| Pro72Pro / T309T | 2 (2) | 2(2) | 1.38 (0.16–11.94) | 0.08/0.77 |
OR odds ratio, CI confidence interval