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. 2017 Nov 1;13(11):e1007088. doi: 10.1371/journal.pgen.1007088

Fig 1. Chromatin association of the DRM complex in late C. elegans embryos.

Fig 1

(A) Model of the C. elegans DRM complex bound to DNA: E2F-DP (blue), the pocket protein LIN-35 (purple), and the 5-subunit MuvB core (green). Subunit interactions and binding of E2F-DP and LIN-54 to CDE and CHR DNA motifs, respectively, are based on [7, 11]. (B) Tier 1: Venn diagrams showing ChIP-seq peak overlaps in wild-type late embryos for E2F-DP (1771 DPL-1 peaks, 2119 EFL-1 peaks), LIN-35 (2291 peaks), and 4 of 5 subunits of the MuvB core (2067 LIN-9 peaks, 2111 LIN-37 peaks, 2284 LIN-52 peaks, 2290 LIN-54 peaks). Tier 2: Venn diagram showing the total peak overlaps between E2F-DP, LIN-35, and MuvB.