Table 5.
Comparison of IL-4 and IL-10 genes with the clinical features in the case group.
| SNP | Genotype | Gender | Age | Duration of fever | CRP (109/L) | WBC count (ρ/mg·L-1) | Neutrophils | Lymphocyte | Monocyte | |
|---|---|---|---|---|---|---|---|---|---|---|
| Male | Female | |||||||||
| IL-4 rs2243283 | CG | 18 | 13 | 41.10± 17.09 | 2.57± 0.41 | 9.03± 0.50 | 6.80± 0.93 | 8.95± 2.14 | 5.35± 1.03 | 3.64± 0.32 |
| CC | 33 | 29 | 38.39± 15.67 | 2.68± 0.43 | 9.18± 0.49 | 7.04± 0.87 | 9.65± 2.29 | 5.59± 1.07 | 3.74± 0.35 | |
| GG | 12 | 7 | 42.84± 15.38 | 2.59± 0.38 | 9.06± 0.46 | 6.87± 0.81 | 9.21± 2.07 | 5.40± 0.97 | 3.67± 0.31 | |
| IL-4 rs2243288 | GG | 14 | 13 | 37.37± 12.64 | 2.12± 0.26 | 8.51± 0.25 | 5.91± 0.67 | 6.52± 1.14 | 4.12± 0.58 | 3.29± 0.12 |
| GA | 32 | 23 | 41.78± 15.94 | 2.61± 0.13* | 9.09± 0.20* | 6.88± 0.23* | 9.28± 0.73* | 5.51± 0.36* | 3.67± 0.3* | |
| AA | 17 | 13 | 38.70± 18.63 | 3.14± 0.26* | 9.71± 0.25* | 7.99± 0.56* | 12.14± 1.07* | 6.69± 0.58* | 4.14± 0.16* | |
| IL-10 rs1800871 | GG | 9 | 9 | 42.11± 16.33 | 2.74± 0.32 | 9.24± 0.41 | 7.20± 0.67 | 10.02± 1.91 | 5.72± 0.79 | 3.79± 0.30 |
| GA | 33 | 27 | 38.21± 16.05 | 2.68± 0.45 | 9.17± 0.52 | 7.05± 0.92 | 9.64± 2.33 | 5.63± 1.09 | 3.75± 0.35 | |
| AA | 21 | 15 | 41.5± 15.84 | 2.51± 0.39 | 9.07± 0.44 | 6.86± 0.78 | 9.17± 2.04 | 5.38± 0.92 | 3.67± 0.29 | |
| IL-10 rs1800872 | GG | 4 | 3 | 37.43± 17.24 | 1.75± 0.20 | 8.15± 0.15 | 4.97± 0.62 | 4.97± 1.03 | 3.30± 0.45 | 3.13± 0.07 |
| GT | 32 | 16 | 41.21± 15.51 | 2.40± 0.15# | 8.80± 0.19# | 6.51± 0.28# | 8.03± 0.96# | 4.87± 0.46# | 3.47± 0.13# | |
| TT | 27 | 30 | 39.09± 16.42 | 2.94± 0.29# | 9.50± 0.30# | 7.56± 0.61# | 11.06± 1.40# | 6.28± 0.61# | 3.97± 0.23# | |
SNP – single nucleotide polymorphism; CRP – C-reactive protein; WBC – white blood cell.