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. Author manuscript; available in PMC: 2017 Nov 13.
Published in final edited form as: Gene. 2016 Mar 3;583(1):48–57. doi: 10.1016/j.gene.2016.02.044

Figure 1. Schematic depiction of SAA1 and its protein sequence variations.

Figure 1

A, linear representation of human SAA1 showing its N-terminal signal peptide of 18 amino acids and the mature SAA1 protein. The 4 α-helices and the C-terminal tail reported recently based on a SAA1.1 crystal structure (Lu et al., 2014) are marked with different colors and their relative positions are indicated. B, comparison of the amino acid sequence encoded by the human SAA1 allelic variants. Mature protein sequences of the 5 human SAA1 variants are shown (based on Sipe et al., 1999). Different amino acids in each of the variants are highlighted in red. Amino acids corresponding to the α-helices and the C-terminal tail are underlined.