Table 3.
Dosimetric parameters | Changes in CTP classification
|
P-value | Hepatic adverse reactions
|
P-value | ||
---|---|---|---|---|---|---|
No | Yes | Grades 0–1 | Grades 2–3 | |||
GTV (mL) | 32.83±27.98 | 25.93±26.13 | 0.510 | 32.82±28.84 | 28.62±22.19 | 0.623 |
Total liver volume (mL) | 1,297.11±263.19 | 1,216.67±345.72 | 0.729 | 1,327.79±273.34 | 1,131.31±194.03 | 0.016 |
Normal liver volume (mL) | 1,246.97±255.86 | 1,217.35±353.27 | 0.768 | 1,277.22±265.37 | 1,086.82±208.44 | 0.018 |
V5 (%) | 61.23±21.30 | 56.36±24.31 | 0.549 | 60.01±21.50 | 63.96±22.15 | 0.552 |
V10 (%) | 35.04±18.65 | 32.12±18.20 | 0.576 | 35.15±18.64 | 37.80±18.51 | 0.642 |
V15 (%) | 22.00±13.88 | 18.87±12.02 | 0.543 | 21.35±13.69 | 23.18±13.94 | 0.664 |
V20 (%) | 14.41±9.39 | 12.88±8.60 | 0.662 | 13.86±9.03 | 16.04±10.51 | 0.445 |
V25 (%) | 10.25±6.95 | 9.23±6.37 | 0.695 | 9.90±6.85 | 11.25±7.09 | 0.524 |
V30 (%) | 7.56±5.43 | 6.62±4.83 | 0.642 | 7.39±5.49 | 7.81±4.86 | 0.800 |
Note: V5, V10, V15, V20, V25, and V30 indicate detailed dosimetric parameters involving the percentage of normal liver volume receiving 5, 10, 15, 20, 25, and 30 Gy, respectively.
Abbreviations: CTP, Child–Turcotte–Pugh; GTV, gross tumor volume; HCC, hepatocellular carcinoma.