Table 2.
Characteristics of antidepressant treatment responders & non-responders (means ± S.D.)
| Responder (N = 20) |
Non-responder (N = 16) |
Significance | |
|---|---|---|---|
| Sex (M/F) | 9/11 | 6/10 |
p = 0.65 (Chi-square test) |
| Age | 34.2 ± 11.7 (range: 28–63) |
47.3 ± 10.3 (range: 19–57) |
p < 0.001 |
| Education (yrs.) | 15.4 ± 2.4 | 16.1 ± 2.4 | p = 0.25 |
| Ethnicity | 17 Caucasian; 2 Asian; 1 South Asian | 1 African; 15 Caucasian | N.A. |
| Co-morbid anxiety | N = 2 (panic disorder; specific phobia) | N = 2 (GAD, PTSD) | N.A. |
| Age of MDD onset | 24.9 ± 14.1 | 30.5 ± 12.9 | p = 0.31 |
| Pre-treatment MADRS | 29.7 ± 4.5 | 30.3 ± 5.9 | p = 0.51 |
| Pre-treatment HAMD17 | 20.4 ± 6.0 | 21.3 ± 3.8 | p = 0.49 |
| Week 12 MADRS | 6.0 ± 5.0 | 23.1 ± 6.8 | p < 0.001 |
| Week 12 HAMD17 | 4.3 ± 3.3 | 15.6 ± 4.4 | p < 0.001 |
GAD: Generalized Anxiety Disorder; HAMD17: 17-Item Hamilton Rating Scale for Depression; MADRS: Montgomery-Åsberg Depression Rating Scale; MDD: major depressive disorder; N.A.: not available; PTSD: Post-Traumatic Stress Disorder.
Note: P values index one-way analyses of variance (ANOVAs), unless stated otherwise.