Figure 4.
EFV increases p38 MAPK phosphorylation and Bax expression. (A) EFV elevates the expression of phospho-p38 in NSCs detected by Western blot. NSCs were plated in 24-well plates for 24 h, treated with 5 μM of EFV or vehicle control (ctrl) for 1 h. Cells were then lysed and subjected to Western blot of phospho-p38 (Ph-p38) and total p38. Each bar is presented as mean ± SEM (**p < 0.01). (B) EFV elevates expression of Bax from NSCs. To detect Bax expression, cells were treated for 24 h with 5 μM of EFV or vehicle control (ctrl). Data are presented as mean ± SEM (*p < 0.05).