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. 2017 Nov 7;26(5):753–763.e7. doi: 10.1016/j.cmet.2017.09.004

Figure 5.

Figure 5

ATGL-Deficient Mice Survive upon Cold Acclimation and Exhibit Normal Brown Adipocyte Recruitment

(A and B) Time course (A) and mean (B) core body temperature (CBT) of ad libitum-fed AKO/cTg mice during cold acclimation at 5°C for 3 weeks using implantable telemetry transmitters (n = 5).

(C) UCP-1 immunoblot of BAT homogenates.

(D) Total protein content from whole BAT depots (n = 3–5).

(E) Calculated total UCP-1 protein amount per BAT of mice housed at 22°C (n = 3) or 5°C for 3 weeks (n = 5).

Analyses were performed in ad libitum-fed male AKO/cTg mice aged 10–12 weeks. Data are presented as means ± SD. Statistical significance was evaluated by unpaired two-tailed Student’s t test. ∗p < 0.05 and ∗∗∗p < 0.001. See also Figure S6.