Table 1.
Mouse Models Used in This Study
| Synonym | Genotype | Reference | ATGL Protein Expressed in: |
|||
|---|---|---|---|---|---|---|
| BAT | WAT | CM | Other Tissues | |||
| AKO | ATGL knockout | Haemmerle et al., 2006 | – | – | – | – |
| iBAKO | inducible BAT-specific ATGL knockout | this study | – | + | + | + |
| AAKO | adipocyte-specific ATGL knockout | Schoiswohl et al., 2015 | – | – | + | + |
| iHAKO | inducible heart-specific ATGL knockout | Kienesberger et al., 2013 | + | + | – | + |
| AKO/cTg | AKO overexpressing a cardiac-specific α-MHC-ATGL transgene | Schreiber et al., 2015 | – | – | + | – |
This table gives an overview of mouse models used in this study and indicates ATGL protein expression in respective tissues. BAT, brown adipose tissue; WAT, white adipose tissue; CM, cardiac muscle; (–) indicates that no ATGL protein is expressed; (+) indicates that ATGL protein is expressed.