Table 1.

Perinatal insults and associated lung disease reported in human subjects.

Perinatal Insult	Associated Lung Disease	Representative References
Intrauterine growth restriction with and without preterm birth	Bronchopulmonary Dysplasia Reduced Lung Function Chronic Obstructive Pulmonary Disease	(Barker et al., 1991, Caudri et al., 2007, Hancox et al., 2009, Kindlund et al., 2010, Jobe, 2012)
Maternal Tobacco Smoke Exposure	Reduced Lung Function Asthma and Wheezing Airway Reactivity	(Gilliland et al., 2003, Jaakkola and Gissler, 2004, Alati et al., 2006, Hylkema and Blacquiere, 2009)
Air Pollution	Asthma Allergic Airway Disease Chronic Obstructive Pulmonary Disease	(Miller and Marty, 2010, Jedrychowski et al., 2013, Wright and Brunst, 2013, Gaffin et al., 2014, Urman et al., 2014)
Maternal Diet	Asthma Allergic Airway Disease	(Erkkola et al., 2009, Checkley et al., 2010, Nwaru et al., 2010)