Table 1.

MA-induced change in temperature relative to saline-treated mice.

Taar1	MA	30 min post-injection (ΔT°C ± SEM)
	(mg/kg)	1st Inj	2nd Inj	3rd Inj	4th Inj
WT	2.5	−2.53 ± 0.37c	−1.91 ± 0.36c	−0.96 ± 0.19b	−0.56 ± 0.26
	5	−2.44 ± 0.27c	−1.98 ± 0.36c	−0.71 ± 0.17a	−0.65 ± 0.22
	10	−1.45 ± 0.17c	−0.99 ± 0.20b	−0.37 ± 0.12	−0.43 ± 0.24
KO	2.5	−0.50 ± 0.20	0.22 ± 0.16	0.40 ± 0.11	0.78 ± 0.13b
	5	−0.83 ± 0.22a	0.24 ± 0.21	0.01 ± 0.17	−0.44 ± 0.21
	10	−0.47 ± 0.16a	0.44 ± 0.14	0.42 ± 0.25	−0.02 ± 0.26

Data represent change in temperature (mean ± SEM) for each treatment group from saline- treated mice at specified time point, n = 11–21 mice per group.

^ap < 0.05;

^bp < 0.01;

^cp < 0.001 in analysis compared to saline-treated controls.