Table 3. Procedural Success Rate, Colonoscopic Polyp Detection Rates, Procedure Times, Recovery Times, Patient and Endoscopist Satisfaction Scores, and Adverse Events72.
| Prevalence | CAPS (n=244) | MF (n=328) | P-value |
|---|---|---|---|
| Procedural success rate (%) | |||
| EGD | 98.2 | 98.7 | 0.958 |
| Colonoscopy | 98.9 | 98.8 | 0.592 |
| Polyp detection rate (%) | 54.5 | 59.3 | 0.666 |
| Patient satisfaction (PSSI scores) | |||
| EGD sedation adequacy | 92.9 | 91.7 | 0.855 |
| Colonoscopy sedation adequacy | 94.8 | 89.9 | 0.002a |
| EGD recovery process | 92.3 | 92.4 | 0.795 |
| Colonoscopy recovery process | 96.0 | 90.1 | <0.001a |
| EGD global satisfaction | 94.8 | 95.4 | 0.704 |
| Colonoscopy global satisfaction | 97.0 | 93.7 | <0.001a |
| Endoscopist satisfaction (CSSI scores) | |||
| EGD recovery process | 89.1 | 69.2 | <0.001a |
| Colonoscopy recovery process | 95.9 | 75.4 | <0.001a |
| EGD global satisfaction | 79.9 | 78.6 | 0.555 |
| Colonoscopy global satisfaction | 94.1 | 83.8 | <0.001a |
| Procedure time (min) | |||
| EGD | 12.5 | 11.3 | 0.183 |
| Colonoscopy | 25.0 | 24.8 | 0.891 |
| Recovery time (min) | 26.4 | 39.1 | <0.001a |
| Overall adverse events (%) | 4.1b,c | 4.0d | 0.910 |
Patient satisfaction was measured using a validated 19-item questionnaire, the Patient Sedation Satisfaction Index (PSSI),73 administered immediately prior to the patient's departure from our unit.
Endoscopist satisfaction was measured using another validated 21-item questionnaire, the Clinician Sedation Satisfaction Index (CSSI),73 administered shortly after each procedure. Scores can range from 0 to 100, with higher scores denoting higher satisfaction.
aSignifies statistically significant P-values.
bIncluding 4 cases of agitation due to undersedation during EGDs, and 2 cases of desaturation, 3 of hypotension and 1 of agitation from undersedation during colonoscopies.
cIn terms of serious adverse events, 1 patient required brief mask ventilation for desaturation during colonoscopy. Another patient had presented with bloody diarrhea and was diagnosed with ischemic colitis during the colonoscopy, dying 14 days after the procedure from sepsis and multi-organ failure (this death was not felt to be caused by the colonoscopy).
dIncluding 3 cases of agitation due to undersedation during EGDs, 2 cases of desaturation, 3 of hypotension and 1 of agitation from undersedation during colonoscopies, and 1 case of hypotension and 2 of agitation due to undersedation.
CAPS, computer-assisted propofol sedation; MF, midazolam fentanyl; EGD, esophagogastroduodenoscopy.