Fig. 3. Median change in CDAI scores over time. In the induction studies and maintenance study, the median change in CDAI scores consistently improved with ustekinumab compared with that with placebo in the Japanese subpopulation and overall study population. All P<0.05 vs. placebo in the overall population of the UNITI-1, UNITI-2, and IM-UNITI studies. q12w, every 12 weeks; q8w, every 8 weeks. Panel B, D, and F are adapted from Feagan BG, et al. N Engl J Med 2016;375:1946-1960, with permission Massachusetts Medical Society.19.
