Skip to main content
. 2017 Oct 23;15(4):475–486. doi: 10.5217/ir.2017.15.4.475

Table 2. Major Secondary Endpoints of Induction Studies in the Overall Population and Japanese Subpopulation.

Endpoints UNITI-1 UNITI-2
Placebo 130 mg ~6 mg/kg Placebo 130 mg ~6 mg/kg
Japan All Japan All Japan All Japan All Japan All Japan All
Number 18 247 19 245 19 249 9 209 8 209 9 209
Clinical response at wk 8 27.8 20.2 21.1 33.5a 52.6 37.8b 0 32.1 37.5 47.4b 66.7 57.9b
Clinical remission at wk 8 5.6 7.3 10.3 15.9a 26.3 20.9b 0 19.6 25.0 30.6a 22.2 40.2b
70-Point response at wk 3 27.8 27.1 42.1 38.4a 42.1 40.6a 11.1 31.6 25.0 49.3b 44.4 50.7b
70-Point response at wk 6 44.4 30.4 42.1 46.1b 52.6 43.8a 11.1 38.8 50.0 58.9b 77.8 64.6b

Values are presented as percentage.

aP<0.01 vs. placebo.

bP<0.001 vs. placebo.