Table 5.
Frequency of adverse drug reactions to anthroposophic medicinal products, subgroup analyses
| All age groups, patients of prescriber physicians | ADRs, all grades | Prescriptions | ADRs/prescriptions (%) | Patients with ADR | Patients with prescription | Patients with ADR/with prescription (%) |
|---|---|---|---|---|---|---|
| All patients of prescriber physicians | 67 | 94,734 | 0.071 | 65 | 12,956 | 0.502 |
| Specific AMPs or AMP groups* | ||||||
| Mistletoe AMPs, ampoules | 3 | 4687 | 0.064 | 3 | 551 | 0.544 |
| Fragaria/Vitis, tablets | 7 | 3322 | 0.211 | 7 | 1771 | 0.395 |
| Apis/Belladonna, dilution | 5 | 2572 | 0.194 | 4 | 2116 | 0.189 |
| Belladonna/Chamomilla recutita, Radix comp., suppositories | 5 | 9717 | 0.051 | 5 | 5100 | 0.098 |
| Hepar sulfuris/Membrana sinuum paranasalium bovis, ampoules | 5 | 1722 | 0.290 | 4 | 1069 | 0.374 |
| Dosage forms | ||||||
| Injectables (parenteral) | 27 | 16,378 | 0.165 | 24 | 3633 | 0.661 |
| Oral | 67 | 53,444 | 0.125 | 58 | 11,660 | 0.497 |
| Local (cutaneous, ophthalmic, rectal, other) | 15 | 24,875 | 0.060 | 15 | 8679 | 0.173 |
| Concentrations | ||||||
| Non-diluted, D1–D3 | 84 | 76,164 | 0.110 | 78 | 12,635 | 0.617 |
| ≥ D4 | 24 | 17,249 | 0.139 | 23 | 6436 | 0.357 |
ADRs adverse drug reactions, AMPs anthroposophic medicinal products
*AMP groups: Mistletoe AMPs