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Factors measured by PRECIS-2 wheel. PRECIS-2 Pragmatic-Explanatory Continuum Indicator Summary 2. Reproduced with permission from BMJ Publishing Group Ltd. from “The PRECIS-2 tool: designing trials that are fit for purpose”; K Loudon, S Treweek, F Sullivan, P Donnan, KE Thorpe, M Zwarenstein; 350:h2147; 2015
