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. 2017 Nov 9;11:102. doi: 10.3389/fnana.2017.00102

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Copyright © 2017 Popovitchenko and Rasin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Balance of differentiation and proliferation. This process ensures that an adequate amount of neurons will be produced. Neurons will be produced through (A) terminal symmetrical division or in a way that the (B) maintenance of the neural progenitor cell pool is ensured with the self-renewal of enough progenitors. Factors guiding each process are listed below. Legend to the right. NSC, neural stem cell; N, neuron; IP, intermediate progenitor; RG, radial glia; Post-transcriptional factors in blue in A and B; TF, transcription factors in red in A and B.